Discomfort and cramping
Omyo GLP-1 Digestive Support
A bedtime two-capsule formula of 22 botanicals, amino acids and zinc, sold for constipation, nausea and bloating on GLP-1 medicines.
- Format
- Capsule, once a day
- Type
- Herbal
- Cost
- $2.00 a day
- Customer rating
- 4.8 out of 5 from 2,814 ratings from omyohealth.com
What customers consistently report
- Regularity returning within days to a few weeks
- Less nausea, burping and bloating
- Small capsules that are easy to take
Those are the themes that recur across the reviews. Low review confidence — the 4.8 from 2,814 reviews is a brand-site widget that says it groups reviews across related products, Amazon shows 5.0 from four ratings all dated the same day on a listing sold by a third party, the brand launched the product in September 2026, and no Trustpilot or Better Business Bureau profile could be read.
Why it might work
The brand’s explanation is that GLP-1 medicines slow digestion and lower bile flow, so food sits and the colon dries out, and that milk thistle, dandelion, beet and artichoke raise bile flow while ginger and artichoke help motility and turmeric and yarrow soothe the gut. The slowing of gastric emptying by GLP-1 medicines is documented; the bile-flow part has no source on the page, and the main biliary finding in trials is a higher rate of gallbladder disease with GLP-1 medicines. Artichoke leaf is listed in herbal references as contraindicated in bile-duct obstruction. Yellow dock root, in the blend, contains the same class of compound (anthraquinones) as senna, although the amount is not printed. The label does not allow a reader to check the dose of any herb in the blend.
What the research supports
No trial of this product or of any named ingredient in GLP-1 constipation was found. Artichoke leaf extract helped functional dyspepsia in a 247-person placebo-controlled trial at 1,920 mg a day, and ginger sped gastric emptying at 1.2 g in an 11-person study; this label lists artichoke at 50 mg and puts ginger and turmeric inside a 571 mg blend of 13 ingredients with no individual amounts. Standard guidance for constipation on GLP-1 medicines centers on fluids, fiber, stool softeners and polyethylene glycol, not on bile-promoting herbs.
What the label discloses
The printed panel lists 22 ingredients, eight of which the page copy that says “14” never names. Nine have amounts, from 30 mg zinc (273% of the daily value) to 50 mg for most herbs and 200 mg for milk thistle, and 13 sit in a 571 mg proprietary blend, so the ginger and turmeric amounts cannot be read. The brand states third-party purity testing and a GMP facility but names no laboratory or manufacturer, and states no allergen information.
Who this tends to suit
We match this product to people reporting constipation, nausea, bloating and general abdominal discomfort. It fits someone whose priority is day-to-day comfort or regularity. Whether it is the best fit for you depends on the rest of your answers — what you have already tried, what format you will take, and anything that has to be ruled out.
Where it may not fit
We hold no dietary claims on file for this product, so we do not assume any. We flag this product for anyone pregnant or breastfeeding or taking prescription medication, and the quiz removes it rather than recommending it in those cases. That is a caution about who should be deciding, not a claim about the product. A capsule only works if you will take it once a day, every day.
Side effects and what to be aware of
Reviewers mostly report relief, with a few saying it did nothing, one saying they can only take it every other day, and several asking to cancel a subscription or citing the monthly cost. The site’s terms say to consult a physician if pregnant, nursing, on medication or with a medical condition; the label carries no printed warnings, although feverfew, yellow dock and artichoke carry pregnancy, bleeding-risk, daisy-family allergy and bile-duct cautions in other references. The page preselects a monthly subscription, and the cancellation-policy link returned an error.
Common questions
Does Omyo GLP-1 Digestive Support work?
No trial of Omyo was found. The brand cites a 2025 customer survey with no sample size, and the herbs it names have been studied for indigestion, not for GLP-1 constipation, at higher doses than this label shows. Reviews on the brand’s own site average 4.8 and are mostly positive; a few people report no effect.
Is Omyo safe with Ozempic, Wegovy, Mounjaro or Zepbound?
The brand says it will not interfere with a GLP-1 medicine, but no interaction study exists and the label prints no warnings. It contains yellow dock (an anthraquinone-containing root), feverfew (bleeding-risk and pregnancy cautions), artichoke (bile-duct and gallstone cautions) and 30 mg of zinc, and GLP-1 medicines themselves raise the risk of gallbladder disease. The brand’s terms say to consult a physician if pregnant, nursing, on medication or with a medical condition.
What are the ingredients in Omyo, and how much of each is in a serving?
A serving of two capsules has 30 mg zinc, 200 mg milk thistle seed, 50 mg each of beet, artichoke leaf, Phyllanthus, dandelion root, chicory root, yarrow and jujube seed, and a 571 mg blend of 13 ingredients including ginger, turmeric, barberry extract, yellow dock, feverfew, alfalfa and burdock with no individual amounts.
How much does Omyo cost, and how does the subscription work?
One bottle (30 days) is $59.99 one time, $2.00 a day, or $39.99 as a monthly auto-refill that is preselected on the page; the page’s own subscription price data lists $49.99. Three bottles are $149.97 one time or $89.99 quarterly. The 60-day guarantee covers the first order only, less $5, and the refund policy says sale items are not returnable.
Who makes Omyo?
The company named in its terms is DTC Labs LLC of Wyoming; the domain was registered in March 2026 and the product page went live on 30 September 2026. No independent complaint record could be read, and no laboratory, manufacturer or certificate is named. Amazon also lists three Omyo products from three different third-party sellers.
Before you take this. Speak to a doctor or pharmacist first if you are pregnant or breastfeeding, or taking prescription medication. Nothing on this page is medical advice, and no supplement diagnoses, treats, cures or prevents disease.
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Related reading
Background on how this type of product works, read from the trial evidence.