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Traditional Chinese medicine

Traditional Chinese medicine and the gut

Traditional Chinese medicine (TCM) treats digestion as the work of what its texts call the spleen and stomach, and most of its best-known digestive formulas are built to support that pair. This section explains the system in plain words, says what the trials of its classic formulas show, sets out the safety record, and lists the TCM products the catalog has researched.

On this page: guides, the system in brief, products, herbs, common questions.

Guides

Are Chinese herbal supplements safe? Aristolochic acid, adulteration, heavy metals and what to check on a label Aristolochic acid, undeclared drugs and heavy metals are documented in Chinese herbal products. In Belgium 18 of 39 patients with the kidney damage had urothelial cancer. Does Chinese herbal medicine work for IBS? The Cochrane review, the JAMA trial and what came after A JAMA trial of 116 people put two herbal formulas ahead of placebo for IBS. The Cochrane review of 75 trials called most of the evidence low quality. Later trials split. Classic Chinese digestive formulas: what the human trials show, formula by formula Eleven classic Chinese digestive formulas and the human trials behind each. The largest placebo trial, of rikkunshito in 247 adults, did not reach significance. Chinese herbal medicine in the United States and Europe: practitioners, products, regulation and evidence Most US states regulate acupuncture and Chinese herbs are sold as supplements. A California survey found 32% of 260 patent medicines held undeclared drugs or metals. Qi, the spleen and food stagnation: the TCM ideas behind gut products, explained 22 TCM terms from qi to teapill, each with its meaning in the tradition and the nearest modern idea, plus what a label that uses them lets a buyer check. What is traditional Chinese medicine, and what does it say about digestion? TCM rests on Han dynasty texts and was standardized in the 1950s. It describes digestion as the work of the spleen and stomach. China had 682,770 practitioners in 2020. Does Health Concerns Quiet Digestion work? A modified Bao He Wan, thirteen herbs and one blend weight Quiet Digestion shares four of the eight herbs in Bao He Wan. Only mouse work tests the formula, and the 45 servings on the label last 15 days at the suggested dose. Does Health Concerns Six Gentlemen work? A Xiang Sha Liu Jun Zi Tang without pinellia or poria, and the dyspepsia trials Six Gentlemen omits pinellia and poria from Liu Jun Zi Tang. Rikkunshito: 33.6% vs 23.8% responders in 247 people (P = 0.09), a benefit in 128 people. Does Snap Dynasty Stomach Chi work? An unnamed eleven-herb blend set against the rikkunshito trials Stomach Chi holds seven of the eight rikkunshito herbs at 3.0 g a day; the trials used 7.5 g of extract. Testing is stated, no lab named. Amazon: 4.5 from 162.

The system in brief

TCM is the modern, standardized form of a medical tradition whose core texts, the Huangdi Neijing and Zhang Zhongjing’s Shang Han Lun, date from roughly the second century BCE to the third century CE. It combines herbal medicine, acupuncture, massage (tuina), diet and movement practices. In China it runs alongside biomedicine in the state health system, with its own universities, hospitals and a national pharmacopoeia; the 2019 edition of the WHO’s international disease classification (ICD-11) added a supplementary chapter of traditional medicine diagnoses drawn from it. In the United States acupuncture is licensed in most states; Chinese herbal medicine is not separately licensed and is practiced under acupuncture and “Oriental medicine” licenses in some states, and the herbs and formulas are sold as dietary supplements under the 1994 DSHEA law, with no pre-market approval of safety or effect. Japan’s Kampo tradition, which uses many of the same formulas in fixed, factory-made granules, is covered by Japanese national health insurance, and some of the best-designed formula trials come from there.

How it describes digestion

TCM describes the body in terms of qi (often glossed as vital energy or function), yin and yang, and a set of organ systems whose names overlap with anatomy but whose definitions are functional. Digestion is assigned to the spleen and stomach: the stomach “receives and ripens” food, the spleen “transforms and transports” it. A practitioner sorts a gut complaint into a pattern rather than a disease: spleen qi deficiency (fatigue, loose stools, bloating after meals), food stagnation (fullness and belching after overeating), damp-heat (urgent, foul loose stools), liver qi overacting on the spleen (bowel symptoms that follow stress). Each pattern has classical formulas: Si Jun Zi Tang and Liu Jun Zi Tang for the deficiency patterns, Bao He Wan for food stagnation, Tong Xie Yao Fang for stress-driven loose stools, Ban Xia Xie Xin Tang for mixed patterns with nausea. Formulas are built from a chief herb with deputies, assistants and an envoy, and are sold as decoctions, granules, teapills and tablets. The herb pages in this section give each ingredient’s pinyin name, the tradition’s classification in plain words and the formulas it belongs to.

What the trials show

Most trials in this field test a multi-herb formula, and most are small, short or poorly reported. A 2006 Cochrane review of herbal medicines for IBS found 75 trials, nearly all from China, and judged the methodological quality generally poor while noting that some formulas improved global symptoms. The best-known Western trial, published in JAMA in 1998, randomized 116 people with IBS in Australia to a standard Chinese formula, an individualized one or placebo for 16 weeks; both herbal groups improved more than placebo, and only the individualized group kept the gain at follow-up. Japanese trials of rikkunshito (Liu Jun Zi Tang) in functional dyspepsia are the most rigorous formula trials for the upper gut. Single herbs with human data include berberine from coptis in IBS-D and diarrhea, rhubarb as a stimulant laxative, and ginger for nausea. The guides below go through the formulas and herbs with the numbers.

Safety: aristolochic acid, adulteration and heavy metals

Three findings shape the safety record. Aristolochic acid, present in Aristolochia species that were substituted for other herbs in some products, caused kidney failure and urinary-tract cancers in a Belgian weight-loss clinic’s patients in the 1990s; the FDA issued a nationwide alert in 2001 and screens imports for it, and the herbs in the catalog’s products are checked against the FDA’s list. Adulteration with undeclared pharmaceuticals and heavy metals has been documented in Asian patent medicines: a 1998 survey of 260 patent medicines sold in California found about a third contained undeclared drugs or heavy metals. Product recalls and FDA warning letters for undeclared drugs continue. Finally, several herbs have documented interactions (ginseng and warfarin, licorice and blood-pressure medicines, bupleurum-containing formulas and interstitial lung disease in Japanese case series). A buyer can check for Latin binomials and pinyin names together, a Supplement Facts panel with amounts, a third-party heavy-metal test, GMP certification, and the absence of any Aristolochia, Asarum or mu tong species that lack a botanical name.

How this site handles TCM products: the same three gates as every other entry (a real rating, a readable Supplement Facts panel, a brand-hosted photo), a check of every ingredient against the FDA’s aristolochic-acid list, the same research page, and a tradition line in the facts box that links back here. The quiz treats them as herbal formulas and nudges them up when someone names Chinese medicine in the free-text box and the symptoms fit.

TCM products in the catalog

Each page names the classical formula where the label gives one, states the label as printed, the trials of the formula, the review picture and the price per day. The products are listed by review count.

Herbs TCM uses for the gut

One page per herb, with its pinyin and Chinese names, the tradition’s classification in plain words, the formulas it belongs to, the human trials, doses and safety. The herb encyclopedia has the full list.

Agastache Agastache rugosa (the Chinese pharmacopoeial huo xiang is Pogostemon cablin) · Huo xiang (Guang huo xiang for Pogostemon; Tu huo xiang for Agastache) Huo xiang is the aromatic lead of Huo Xiang Zheng Qi; its oral liquid beat placebo in a 212-person IBS-D trial (response gap 0.29), but the herb alone is untested. Aloe vera Aloe vera (L.) Burm.f. (Aloe barbadensis Miller) · Lu hui (the dried juice) Two materials: clear inner-leaf gel and aloin-rich latex. FDA removed aloe latex from OTC laxatives in 2002; NTP found large-bowel cancers in rats on whole-leaf extract. Amomum (sha ren) Wurfbainia villosa (syn. Amomum villosum) · Sha ren A ginger-family seed used in Chinese stomach formulas; no trial of it alone, and a 216-adult placebo-controlled trial of an eight-herb formula that contains it. Astragalus Astragalus mongholicus (syn. A. membranaceus) · Huang qi Astragalus root (huang qi) has no gut trial on its own; a 13-trial meta-analysis of an astragalus formula in atrophic gastritis gave RR 1.24. Atractylodes Atractylodes macrocephala (bai zhu); A. lancea (cang zhu) · Bai zhu (A. macrocephala), Cang zhu (A. lancea) Bai zhu leads the classic Chinese spleen formulas; a 96-person IBS-D trial of Tong Xie Yao Fang found 79.2% vs 70.8% response, not significant. Aucklandia (costus root) Aucklandia costus (syn. Aucklandia lappa, Saussurea costus) · Mu xiang (also Guang mu xiang) Costus root, named in 145 pharmacopoeia preparations; no human trial of it alone, and a 23-study review of one formula that contains it (RR 1.27). Barley sprout (mai ya) Hordeum vulgare · Mai ya Sprouted barley, a digestion herb in Zhi Shi Xiao Pi Wan; the trials with numbers test a different barley fiber product in colitis (59 patients, 12 months). Berberine Berberis, Hydrastis, Coptis and Mahonia species (source plants) · Huang lian (coptis rhizome, a berberine-rich source) An alkaloid from barberry, goldenseal and coptis. One IBS-D trial used 400 mg a day for 8 weeks; it also changes how the body handles several medicines. Bitter orange Citrus aurantium · Zhi shi (immature fruit), Zhi ke or Zhi qiao (more mature fruit) Two Chinese fruit drugs, one weight-loss ingredient: a 21-trial review of the zhi shi formula (OR 3.54) and, for synephrine, a 6.4 mmHg rise in systolic pressure. Black pepper Piper nigrum · Maricha A pungent spice whose alkaloid piperine raised curcumin absorption 2,000 percent in one human study; no trial has tested pepper for digestive symptoms. Bupleurum Bupleurum chinense · Chai hu Bupleurum (chai hu) leads Xiao Yao San (6 dyspepsia trials, RR 1.15 vs drugs); the Kampo formula sho-saiko-to was behind 26% of 73 reported herbal pneumonitis cases. Burdock Arctium lappa · Niu bang zi (fruit); Niu bang gen (root) A root eaten as a vegetable; Chinese medicine uses the fruit. EMA lists a traditional use for appetite, found no clinical studies; the root is about 45 percent inulin. Cardamom Elettaria cardamomum (small or green cardamom); Amomum species in Chinese medicine · Ela (Sukshma ela) A fragrant spice pod. In two small postoperative trials, cardamom oil (inhaled or sublingual) lessened nausea; we found no trial of it for indigestion. Chinese yam Dioscorea oppositifolia (also written Dioscorea opposita) · Shan yao A mild starchy root eaten as food and simmered in spleen formulas; a review found only two human trials of it among 27 studies. Cinnamon Cinnamomum verum (Ceylon) and Cinnamomum cassia and related species (cassia) · Twak, Tvak Two barks sold as cinnamon: Ceylon (low coumarin) and cassia (about 3 g coumarin per kg on average). No trial has tested either for a gut symptom. Clove Syzygium aromaticum · Lavanga Warming spice used in Ayurveda and Chinese medicine for nausea and cold stomach pain. We found no human gut trial; 10 ml of the oil caused liver failure in a toddler. Codonopsis Codonopsis pilosula · Dang shen Codonopsis (dang shen) is the milder root that stands beside ginseng in Chinese spleen formulas; we found no gut trial of it alone, only mixed-formula data. Coix Coix lacryma-jobi var. ma-yuen · Yi yi ren A pale grain eaten as food and used in spleen formulas; the only gut-adjacent human data we found are 11 men eating 160 g a day for 7 days. Coptis Coptis chinensis · Huang lian Coptis (huang lian) is the rhizome that supplies berberine; berberine hydrochloride cut diarrhea and pain frequency in a 132-person IBS-D trial (p = 0.032 and p < 0.01). Dandelion Taraxacum officinale (and T. mongolicum in Chinese medicine) · Pu gong ying A bitter weed used in Europe for fullness and poor appetite. EMA found no clinical studies; its monograph rests on traditional use (4 to 10 g as an infusion). Dang gui (Chinese angelica) Angelica sinensis · Dang gui The classic blood-nourishing root, listed in the texts as lubricating the intestines; we found no gut trial of it, and one case of it doubling a warfarin reading. Evodia (wu zhu yu) Tetradium ruticarpum (syn. Evodia rutaecarpa) · Wu zhu yu A hot, bitter fruit the texts call slightly toxic; the one human gut study we found is 14 patients on Zuo Jin Wan, and the lab record includes liver injury. Fennel Foeniculum vulgare · Madhurika, Mishreya The seed chewed after meals; one infant colic trial (125 babies) found colic gone in 65% vs 23.7% on placebo, and adult gut trials are of mixtures. Garlic Allium sativum · Lasuna, Rasona Kitchen bulb sold as capsules and extract. For gut infections the human data are small pilots and an add-on meta-analysis of allicin (93% vs 84% H. pylori eradication). Ginger Zingiber officinale · Shunthi (dried), Ardraka (fresh) A kitchen rhizome with the best gut evidence of any herb for nausea: 12 pregnancy trials (1,278 women) found lower nausea scores than placebo. Ginseng Panax ginseng · Ren shen (white), Hong shen (red) Ginseng has no gut-outcome trial on its own; it sits in rikkunshito, where a 247-person dyspepsia trial found 33.6% vs 23.8% responders, not significant. Hawthorn Crataegus pinnatifida (shan zha); Crataegus monogyna and C. laevigata (Western) · Shan zha Hawthorn fruit is the Chinese herb for meat and grease stagnation (9 to 12 g in the Pharmacopoeia); we could find no human gut trial, and it interacts with heart drugs. Jujube Ziziphus jujuba · Da zao The sweet red date of Chinese cooking and formulas; one 12-week placebo trial of a liquid extract in 37 constipated adults, and a children&rsquo;s trial of a syrup. Licorice Glycyrrhiza glabra · Yashtimadhu, Madhuyashti Whole root and DGL are different products: 18 studies show whole root raising systolic pressure 5.45 mmHg; a DGL ulcer trial found no healing effect. Lotus seed Nelumbo nucifera · Lian zi A food seed that the texts use to firm loose stools, in Shen Ling Bai Zhu San; we found no gut trial of it, and one 45-adult trial of an extract for depression. Magnolia bark Magnolia officinalis · Hou po Magnolia bark (hou po) is the bark behind Ping Wei San and Da Cheng Qi Tang; we found no gut trial of it alone, only formula trials and a mouse ileus study. Massa fermentata (shen qu) Massa Medicata Fermentata (a fermented mixture, not a single plant) · Shen qu (the standard type is Liu shen qu) A fermented herbal cake that the tradition uses for food stagnation; we found no human trial of it, only rat and mouse studies and a classical formula. Orange peel Citrus reticulata (chen pi); Citrus sinensis (sweet orange); Citrus aurantium (bitter orange) · Chen pi Orange and tangerine peel is the TCM herb chen pi (3 to 10 g) and a Western bitter; we could find no human trial of the peel alone for gut outcomes. Perilla Perilla frutescens · Zi su ye (leaf), Zi su geng (stem), Zi su zi (seed) Perilla leaf (zi su ye) is an aromatic leaf in Huo Xiang Zheng Qi; the formula beat placebo in a 212-person IBS-D trial (response gap 0.29); perilla alone is untested. Pinellia Pinellia ternata · Ban xia (Fa ban xia, Jiang ban xia and Qing ban xia are the processed forms) Pinellia (ban xia) is used processed because the raw tuber irritates the mouth; 57 trials of Ban Xia Xie Xin Tang in dyspepsia (5,525 people) favored it over drugs. Poria Wolfiporia cocos (syn. Poria cocos) · Fu ling Poria (fu ling) is a fungus in five classic Chinese digestive formulas; 14 trials of Shen Ling Bai Zhu San in chronic diarrhea (1,158 adults) found higher satisfaction. Pu-erh tea Camellia sinensis (post-fermented Yunnan tea) · Pu'er cha The aged tea drunk after greasy meals; its trials are of lipids and weight, not digestion: 90 adults with metabolic syndrome, 36 on 333 mg of extract. Radish seed (lai fu zi) Raphanus sativus · Lai fu zi The seed of the garden radish, a food-stagnation herb in Bao He Wan; a review found no human gut trials, and a cell study suggests it blocks ginseng absorption. Rhubarb root Rheum palmatum; Rheum officinale · Da huang Rhubarb root (da huang) is a stimulant laxative; a 42-person trial used 12.5 or 25 mg of rhein a day for 30 days, while the EU monograph caps use at 1 week. Schisandra Schisandra chinensis (bei wu wei zi); Schisandra sphenanthera (nan wu wei zi) · Wu wei zi Schisandra (wu wei zi) is a TCM astringent listed for chronic diarrhea at 2 to 6 g; its human data are on liver enzymes, and we found no gut trial of the herb alone. Turmeric Curcuma longa · Haridra In 132 people with dyspepsia, turmeric lowered pain scores more than placebo and similarly to omeprazole; liver injury and lead adulteration are documented. White peony Paeonia lactiflora · Bai shao White peony (bai shao) is the texts&rsquo; pain herb in Tong Xie Yao Fang; that formula&rsquo;s 96-person IBS-D trial found 79.2% vs 70.8% response, not significant.

Which product fits your symptoms?

The quiz asks about your symptoms, what you have tried and the medicines you take. Name Chinese medicine in the free-text box and its formulas get a nudge in the ranking when they fit.

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Common questions

Is Chinese herbal medicine regulated in the United States?

The herbs and formulas are dietary supplements under the 1994 DSHEA law, so they need no pre-market approval; the FDA acts after the fact on adulteration, contamination and illegal claims, and holds import alerts for aristolochic acid and for some brands. Practitioners: acupuncture is licensed in most states, and Chinese herbal medicine is practiced under those licenses in some of them; there is no separate herbalist license.

What is the difference between a patent medicine, a teapill and granules?

A patent medicine is a fixed classical or proprietary formula sold ready-made, usually as small pills (teapills) or tablets. Granules are concentrated extracts dried onto a carrier and dissolved in hot water, the form Japanese Kampo and many US practitioners use. A decoction is the raw herbs simmered at home, the traditional form, and the one most classical doses refer to.

Do TCM formulas work for IBS?

The 2006 Cochrane review found that some formulas improved global IBS symptoms across 75 mostly Chinese trials but rated the evidence low in quality. The one Western placebo-controlled trial (116 people, 16 weeks, JAMA 1998) found benefit for both a standard and an individualized formula. That is a reason to call the evidence suggestive, not settled; the guides give the trials.

What is aristolochic acid and should I worry about it?

A kidney toxin and carcinogen in Aristolochia plants, which were substituted for other herbs in some products in the 1990s and caused kidney failure in Belgium and elsewhere. The FDA has screened imports for it since 2001. Products from brands that publish botanical names and testing are the practical safeguard; none of the catalog’s products contains an Aristolochia species.

What does spleen qi deficiency mean?

It is a TCM pattern, not a statement about the anatomical spleen. The texts use it for a cluster of fatigue, poor appetite, bloating after meals and loose stools, and treat it with formulas such as Si Jun Zi Tang and Liu Jun Zi Tang. The key-concepts guide goes through the patterns and their formulas.

How does the quiz treat TCM products?

As herbal formulas scored on the same symptoms, trials, label and review criteria as everything else. If you write Chinese medicine, TCM or a formula name in the free-text box, products carrying the TCM tradition flag get a small boost when they fit your symptoms. Nothing is excluded because of its tradition.

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