Daily gut routine
Akka Liver and Gut Superbiotic
A two-capsule daily formula of pasteurized Akkermansia with milk thistle, artichoke, quercetin and resveratrol, sold for liver and digestive support.
- Format
- Capsule, once a day
- Type
- Postbiotic and herbal
- Cost
- $2.13 a day
- Customer rating
- 4.4 out of 5 from 1,107 ratings from Amazon
What customers consistently report
- Less bloating and smoother digestion within a few weeks
- Steadier energy through the day
- Capsules that are easy to swallow with no taste or smell
Those are the themes that recur across the reviews. Low review confidence — the 4.4 from 1,107 ratings is on Amazon where the brand is the seller, the 4.7 from 272 reviews on the brand’s own store is a self-hosted widget, and Trustpilot shows 2.9 from 42 reviews for the ad site and 1.9 for the parent store, with billing and refund complaints.
Why it might work
The brand’s idea is that pasteurized Akkermansia strengthens the gut lining and the gut-to-liver signal, while silymarin and artichoke are traditional liver and bile ingredients and quercetin and resveratrol add antioxidant support. In trials, heat-treated Akkermansia changed blood sugar and cholesterol markers in people with metabolic syndrome, but a trial for gut symptoms was not found. Artichoke increases bile flow, and silymarin, quercetin and resveratrol can affect how some medicines are processed. The label cannot show whether the 3 billion units match the amounts that worked in trials, because the trials counted cells of a different strain.
What the research supports
No trial of this formula was found. The human evidence for pasteurized Akkermansia is a 2019 pilot of 32 adults with metabolic syndrome, where 10 billion pasteurized cells a day for three months improved insulin sensitivity by about 29% and lowered the liver enzyme gamma-GT by about 24% against placebo, and a 2026 trial of 142 adults at 30 billion cells did not meet its main insulin-sensitivity endpoint. Both used the MucT strain; this label uses AH39 at 3 billion units, and no human trial of AH39 was found. The four botanicals have trials in fatty liver at similar or higher doses (artichoke 600 mg, quercetin 500 mg, resveratrol 500 to 3,000 mg), and the label amounts are about half or less of those.
What the label discloses
Each ingredient has its own amount, which is more than most multi-ingredient labels give, and the Akkermansia strain (AH39) and count (3 billion TFU) are named. The panel does not say pasteurized; the brand’s pages do, and the TFU unit is the one used for heat-treated cells, so the count is not comparable with a live product’s CFU or AFU. The brand states a GMP facility and ingredient testing, but no laboratory, certificate or manufacturer was found.
Who this tends to suit
We match this product to people reporting bloating and general abdominal discomfort. It fits someone whose priority is a steady daily routine or resetting after a course of antibiotics or an upset. Whether it is the best fit for you depends on the rest of your answers — what you have already tried, what format you will take, and anything that has to be ruled out.
Where it may not fit
The label supports gluten-free, dairy-free and no added sweeteners. We flag this product for anyone pregnant or breastfeeding or taking prescription medication, and the quiz removes it rather than recommending it in those cases. That is a caution about who should be deciding, not a claim about the product. A capsule only works if you will take it once a day, every day.
Side effects and what to be aware of
Reviewers on Amazon are mostly positive (71% five-star), with a minority reporting no effect or the price; Trustpilot is far lower, with reports of duplicate charges, extra bottles and refund disputes. The label says to consult a physician if pregnant, nursing, under 18 or with a medical condition. Artichoke and milk thistle are both in the daisy family (ragweed allergy), and artichoke carries a caution for bile-duct blockage and gallstones in drug references. The ad site preselects a subscription.
Common questions
Does Akka work?
No trial of Akka itself was found. The brand cites a 2019 pilot of pasteurized Akkermansia in 32 adults with metabolic syndrome, which found better insulin sensitivity and lower gamma-GT at 10 billion cells a day of a different strain (MucT); a 2026 trial of 142 adults did not meet its main endpoint. Akka’s dose is 3 billion units of strain AH39, and the liver claims rest mainly on animal studies. Amazon buyers rate it 4.4 from 1,107 ratings, while Trustpilot shows 2.9 from 42 reviews, many saying they saw no change.
Is Akka safe, and what are the side effects?
The label says to consult a physician if pregnant, nursing, under 18 or with a medical condition, and the brand adds taking medication. Artichoke carries a bile-duct blockage and gallstone caution in drug references, milk thistle and artichoke can trigger reactions in people allergic to ragweed and daisies, and quercetin and resveratrol have reported interactions with blood thinners and some prescription drugs. Reviewers mention an upset stomach if taken on an empty stomach.
Akka vs Pendulum Akkermansia: what is the difference?
Pendulum is a single live strain (WB-STR-0001, 100 million AFU, one capsule a day) with inulin. Akka is a pasteurized strain (AH39, 3 billion TFU, two capsules a day) plus milk thistle 400 mg, artichoke 300 mg, quercetin 250 mg and resveratrol 150 mg. The counts use different units and cannot be compared directly. Akka costs about $2.13 a day on Amazon, Pendulum about $2.17.
How much does Akka cost?
One 60-capsule bottle (30 days) is $64.00 on Amazon ($2.13 a day), $59 plus $4.95 shipping on the parent store, and $69.99 at GNC. The ad site lists $69 and shows subscription prices of $50 monthly, $42 a bottle every 90 days and $33 a bottle every 180 days, with the subscription option selected by default.
Who makes Akka, and what is the refund policy?
Akka is sold by Konscious Brands, trading as Enclave BioActives, of San Juan, Puerto Rico, and the doctor it names, Gina Sam, is a licensed New York gastroenterologist. The brand offers a 90-day money-back guarantee; single bottles need no return, multipacks require sending back unopened bottles, and shipping and handling fees can be deducted. Trustpilot reviewers describe duplicate or extra charges and disputed refund windows.
Before you take this. Speak to a doctor or pharmacist first if you are pregnant or breastfeeding, or taking prescription medication. Nothing on this page is medical advice, and no supplement diagnoses, treats, cures or prevents disease.
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Related reading
Background on how this type of product works, read from the trial evidence.