Discomfort and cramping
Inno Supps Inno Cleanse
A two-capsule herbal blend of senna, cascara, cape aloe and frangula, four stimulant laxatives, taken in 14-day courses for bloating and irregularity.
- Format
- Capsule, once a day
- Type
- Herbal
- Cost
- $1.33 a day
- Customer rating
- 4.1 out of 5 from 12,407 ratings from Amazon
What customers consistently report
- A bowel movement within a day or two
- Less bloating for many users
- Quick customer service when cancelling an order
Those are the themes that recur across the reviews. Moderate review confidence — Amazon shows 4.1 from 12,407 ratings and Trustpilot 4.1 from 1,486 reviews, both independent, but the Trustpilot figure covers the whole Inno Supps store and 31% of it is one-star, mostly about orders and billing, and the brand’s own count of five-star reviews cannot be traced to a platform.
Why it might work
Senna, cascara, aloe latex and frangula bark are anthranoid laxatives: gut bacteria release the active compounds in the colon, where they stimulate the bowel wall and reduce water absorption, producing a bowel movement within hours. The same compounds are why standard OTC senna labels say not to use laxatives for longer than one week without a doctor, and why the FDA excluded aloe and cascara from its OTC laxative list in 2002 for lack of safety data. Fennel and bentonite are listed for digestion, burdock, licorice and slippery elm for soothing, and milk thistle and capsicum sit in a 40 mg blend; none has a trial at these doses. Licorice can lower potassium, which matters more alongside a laxative. The label says to take two capsules a day for 14 days once a month, and nothing on it lets you check how much of any herb you get.
What the research supports
The evidence is for the ingredient class, not this formula. A placebo-controlled trial of senna at 1.0 g a day for 28 days in 90 adults with chronic constipation found 69.2% improved against 11.7% on placebo, but this label prints one 824 mg figure for senna, cascara, aloe and frangula together. A 30-person, 2-week placebo-controlled trial of Inno Cleanse itself is registered at the University of Memphis (NCT07215351) and completed in July 2026 with no results published, and no trial of the other herbs for bloating was found.
What the label discloses
Eleven herbs and a clay sit in four proprietary blends, so the dose of each laxative herb is not printed. The brand lists third-party testing in a comparison table but names no laboratory, and the Amazon ingredient field shows another product’s ingredients. The facility statement lists eight major allergens handled on shared equipment.
Where it may not fit
We hold no dietary claims on file for this product, so we do not assume any. We flag this product for anyone pregnant or breastfeeding or taking prescription medication, which is a caution about who should be deciding, not a claim about the product. A capsule only works if you will take it once a day, every day.
Side effects and what to be aware of
The most common complaints are about billing: trial offers, subscription cancellation fees or repricing, and charges after cancelling, concentrated in the brand’s Trustpilot one-star reviews. Amazon’s review summary mentions severe cramping for some users. The label text that could be read shows no pregnancy, medication, diarrhea or duration warning, while an OTC senna label says not to use for longer than one week unless a doctor directs it, and the brand’s own trial excluded people with diabetes, high blood pressure, heart or bowel disease, pregnancy and many medicines.
Common questions
Does Inno Cleanse work?
It contains senna, cascara, cape aloe and frangula, which are stimulant laxatives, and senna at 1.0 g a day beat placebo for constipation in a 28-day trial of 90 adults (69.2% against 11.7% improved). The label does not print how much senna it contains, and no trial of bloating relief has been published for any ingredient. A 30-person trial of Inno Cleanse itself finished in July 2026 and has no published results.
Is Inno Cleanse safe, and what are the side effects?
The label says to take two capsules a day for 14 days at a time once a month, while an OTC senna label says not to use laxatives for longer than one week unless a doctor directs it. Cramping, diarrhea and electrolyte loss are the known effects of this class, and Amazon’s review summary mentions severe cramping for some users. No pregnancy, medication or kidney warning was found on the label text, and the sponsor’s own trial excluded people with diabetes, high blood pressure, heart disease, bowel disease, pregnancy and many medicines.
Is Inno Cleanse a laxative?
It is sold as a dietary supplement with a Supplement Facts panel, not as an OTC drug, but four of its ingredients (cascara sagrada, cape aloe, senna and frangula) are stimulant laxatives, and the brand’s own page calls cape aloe a mild natural laxative. The FDA decided in 2002 that aloe and cascara are not generally recognized as safe and effective as OTC laxative ingredients, so they are not in drugstore laxatives, though they remain in supplements.
How much does Inno Cleanse cost?
One 60-capsule bottle is $39.99 on the brand site ($1.33 a day at two capsules), $31.99 on its Subscribe & Save plan delivered every 28 days, and $38.97 on Amazon ($35.07 with Subscribe & Save). Used as the label directs, 14 days a month, one bottle covers two courses, so a 28-day subscription ships more than a label-following user needs.
How do I cancel an Inno Supps subscription or get a refund?
Inno Supps has a 4.1 Trustpilot score from 1,486 reviews, but 31% are one-star, and those are mostly about trial offers, cancellation charges and shipping. Its terms set a two-shipment minimum for the subscription discount (cancel before the second and the first is repriced to $39.99), and its refund policy words the 100% guarantee around two other products, with the rest refundable if less than half is used. Cancel through the account page, by email or by chat before the next processing date.
Before you take this. Speak to a doctor or pharmacist first if you are pregnant or breastfeeding, or taking prescription medication. Nothing on this page is medical advice, and no supplement diagnoses, treats, cures or prevents disease.
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Related reading
Background on how this type of product works, read from the trial evidence.