Discomfort and cramping
Liver Medic Leaky Gut Repair
A two-capsule bedtime formula of zinc and a nine-ingredient blend led by L-glutamine, slippery elm, marshmallow root and DGL.
- Format
- Capsule, once a day
- Type
- Amino acid, herbal and DGL licorice (mucosal protectant)
- Cost
- $1.00 per day at two capsules; the label’s advanced dose of four to six is $2.00 to $3.00
- Customer rating
- 4.1 out of 5 from 3,474 ratings from Amazon
What customers consistently report
- Less bloating, cramping and heartburn within days
- Being able to eat foods they had cut out
- Easy-to-swallow capsules with no aftertaste
Those are the themes that recur across the reviews. Moderate review confidence — Amazon shows 4.1 from 3,474 independent ratings, but the brand’s own 4.6 from 375 comes from a review app where only 68 are marked verified and some are imported from Amazon, the home page’s typed 12,000+ is not a review count, and the Trustpilot profile (4.5 from 62) covers the whole brand with no review in the last year.
Why it might work
The idea behind products sold for a “leaky gut” is that the lining of the small intestine can become more permeable and that giving the cells building blocks and a protective coating helps it recover. Glutamine is an amino acid that intestinal cells use as fuel, zinc is needed for the lining’s repair, slippery elm and marshmallow root are mucilage plants that form a slippery gel, and DGL is licorice with the glycyrrhizin removed. Quercetin, bromelain, MSM, NAG and aloe are added for calming or structural roles that the label does not let you check. In trials, glutamine’s effect on permeability appeared at doses far above what a blend this size can hold, and increased permeability is a laboratory finding rather than a diagnosis used in everyday care. The label shows no individual amounts, so the formula’s real dose of each ingredient cannot be compared with any trial.
What the research supports
No trial of this formula was found. The largest glutamine trial is one placebo-controlled trial of 106 adults with post-infectious IBS-D and raised gut permeability, where 15 g a day for 8 weeks brought 79.6% of the glutamine group to a 50-point symptom improvement against 5.8% on placebo; a 10-trial meta-analysis found no overall change in permeability and a benefit only above 30 g a day. This label puts L-glutamine in a 981 mg blend with eight other ingredients, so it supplies at most about 6.5% of the trial dose, and its zinc is zinc orotate, not the zinc carnosine used in the one small crossover trial in 10 volunteers. Slippery elm has only uncontrolled combination-formula studies.
What the label discloses
Zinc is the only ingredient with its own amount (25 mg, 227% of the Daily Value); the nine others share a 981.26 mg proprietary blend, so the amount of glutamine, slippery elm, marshmallow, NAG, DGL, aloe, MSM, quercetin and bromelain is unknown, and the aloe leaf powder has no stated form or aloin level. The panel states that it contains shellfish, and a shellfish-free version is sold at the same price. The brand states GMP, an NSF-registered facility and third-party testing, but names no laboratory and posts no certificate.
Who this tends to suit
We match this product to people reporting bloating, general abdominal discomfort, heartburn or reflux, loose stools and constipation. It fits someone whose priority is day-to-day comfort or resetting after a course of antibiotics or an upset. Whether it is the best fit for you depends on the rest of your answers — what you have already tried, what format you will take, and anything that has to be ruled out.
Where it may not fit
The label supports gluten-free. We flag this product for anyone pregnant or breastfeeding or taking prescription medication, and the quiz removes it rather than recommending it in those cases. That is a caution about who should be deciding, not a claim about the product. A capsule only works if you will take it once a day, every day.
Side effects and what to be aware of
Amazon reviewers split on value and effect, with some feeling nauseous, one reporting a reaction they attribute to MSM and a sulfa allergy, and one calling it expensive for a 2-week supply at the higher dose. The panel states it contains shellfish, and the page says to consult a physician if pregnant, nursing, taking medication or with a medical condition.
Common questions
Does Liver Medic Leaky Gut Repair work?
No trial of this formula was found. Amazon shows 4.1 from 3,474 ratings (57% five-star, 8% one-star), and reviewers describe less bloating and heartburn, while others report little effect. The largest glutamine trial used 15 g a day; this label has a 981 mg blend of nine ingredients per serving.
What is in Leaky Gut Repair, and how much glutamine does it have?
Two capsules have zinc (as zinc orotate) 25 mg and a 981.26 mg blend of L-glutamine, organic slippery elm, organic marshmallow root, N-acetyl-D-glucosamine, licorice root extract (DGL), aloe vera leaf powder, MSM, quercetin and bromelain, with no amount for each. Glutamine therefore cannot exceed 981 mg a serving. It contains shellfish.
How much does Leaky Gut Repair cost per day?
A 60-capsule bottle is $29.99 on the brand site and on Amazon, which is 30 servings of 2 capsules, or $1.00 a day; Amazon Subscribe & Save is $26.99 ($0.90). At the label’s advanced dose of 4 to 6 capsules a day, a bottle lasts 10 to 15 days and costs $2.00 to $3.00 a day.
Does it contain zinc carnosine, and what side effects are reported?
No: the zinc is zinc orotate at 25 mg, and zinc carnosine, studied in a small trial in 10 volunteers, is not in the panel. Amazon’s summary says some feel nauseous, one reviewer reported a reaction they linked to MSM and a sulfa allergy, and the panel states it contains shellfish. The page says to consult a physician if pregnant, nursing or taking medication.
Where does Liver Medic’s 12,000+ reviews figure come from, and what is the refund policy?
The home page’s 4.8 from 12,000+ is text with no review app behind it; the product page’s review app shows 4.6 from 375 with 68 marked verified, Amazon shows 4.1 from 3,474, and Trustpilot shows 4.5 from 62 with none in the last year. The brand states a 90-day return policy that asks for a return authorization and unused product in its original packaging.
Before you take this. Speak to a doctor or pharmacist first if you are pregnant or breastfeeding, or taking prescription medication. Nothing on this page is medical advice, and no supplement diagnoses, treats, cures or prevents disease.
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Related reading
Background on how this type of product works, read from the trial evidence.